[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
May 4, 1889


JAMA. 1889;XII(18):624-628. doi:10.1001/jama.1889.02400950012003

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


Glycerine Suppositories.  Polübinsky concludes the eccoprotic action of the drug cannot possibly be attributed to anything like its softening or liquefying fœcal masses, since (a) water, milk, olive oil, and other fluids, when injected into the rectum in similarly small quantities (6 grams or so) fail to excite any motions; (b) when injected in such trifling doses, glycerine is rapidly absorbed by the mucous membrane; (c) stools occurring after glycerine enemata are usually solid and sausage-shaped—that is, show no signs of liquefaction; (d) neither are the masses covered with any watery or slimy layer; (e) stools take place within a short time after the administration of glycerine, while the liquefaction process should necessarily require a comparatively long interval. 2. Glycerine undoubtedly causes a local irritation (probably congestion) of the rectal mucous membrane, since (a) all patients experience a sensation of warmth or some burning in the rectum; (b) there

First Page Preview View Large
First page PDF preview
First page PDF preview