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January 4, 1890


JAMA. 1890;XIV(1):31-33. doi:10.1001/jama.1890.02410010043011

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Chloralamid—Lepers and Leprosy in Norway— A Myxoma Springing from the Infra-orbital Nerve — Does Moderate Drinking and Long Life go Naturally Together?—Miscellaneous Items.

Some recent experiments with the new hypnotic, chloralamid, on frogs and rabbits tend to show that the drug is completely harmless to animals; also that the blood pressure is not materially altered. This being the case, the drug has been tried on a few patients who complained of sleeplessness. The sleep after chloralamid was deep and refreshing; its duration varied, according to individuality, between six and ten hours. The patients awoke without feeling the slightest indisposition, without headache or indigestion, or bad taste in the mouth, as frequently observed after chloralhydrate. Even very delicate patients with weak stomach did well with chloralamid, which is stated to be due to the fact that the drug is non-irritant to mucous membranes, not even to those of the most delicate

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