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August 22, 1891


JAMA. 1891;XVII(8):309-310. doi:10.1001/jama.1891.02410860033002

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The lectures delivered at the post-graduate course at Toronto last winter, have reached us in pamphlet form. Among them is one by Prof. Victor C. Vaughan under the above caption. After reviewing the work which has been done by various investigators as to the presence of the Koch-Eberth germ in typhoid fever, and the attempts to inoculate lower animals with it, he sums up as follows:

  1. A germ giving the tests supposed to be characteristic of the Eberth germ is found invariably in the bodies of those dead from typhoid fever.

  2. It has been isolated and grown in pure cultures.

  3. All attempts to induce typhoid fever in the lower animals by inoculation with this germ have so far been without success.

  4. Experiments shownot only that the germ fails to multiply in the lower animals, but that, when introduced by inoculation, it soon dies.

The failure of the inoculation experiments may

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