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January 7, 1911

THE TREATMENT OF ECLAMPSIA: INCLUDING A COMPARISON OF THE DANGERS OF CHLOROFORM AND ETHER IN THIS CONDITION

JAMA. 1911;LVI(1):5-11. doi:10.1001/jama.1911.02560010007002
Abstract

In all branches of medicine to-day the prophylactic treatment, or preventive medicine, receives foremost consideration. Hence it is that in the treatment of eclampsia the toxemia of pregnancy, which threatens and may, or may not, eventuate in an eclamptic seizure, demands our chief attention. Whatever the exact etiology may prove eventually to be, it is generally agreed that the symptoms and pathologic changes of the toxemia of pregnancy and the puerperium are caused by some toxin or toxins circulating through the system, and that with this there is associated some fault in the elimination of the products of metabolism.

Accepting this as a working basis of etiology, the obstetrician may well be guided in treatment of toxemia threatening eclampsia by these five principles:

  1. The products of metabolism requiring elimination should be reduced.

  2. Elimination of metabolic products should be favored.

  3. High blood-pressure should be reduced.

  4. If the toxemia of the patient,

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