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January 28, 1911


JAMA. 1911;LVI(4):273. doi:10.1001/jama.1911.02560040041023

That vital activity, in the broadest sense of the term, is most intimately associated with enzyme action, is a matter of common acceptation. In view of this, the investigation of the part played by ferments in pathologic processes has become of no small significance. In a recent article, Wohlgemuth1 outlines the general progress that has been made in this direction. To review in detail the great amount of valuable work being done on this subject, both here and abroad, would be impossible at this time, and the present review is based solely on the account just cited. Practically only the borderland of this enormous field has been entered, and yet results have been obtained that indicate unmistakably the value of further work.

As would be expected a priori, different ferments occur in different tissues in varying proportions. So, for instance, oxidase appears to occur in proportion to the presence