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It has been known for some time that the motility of the stomach is usually increased and that the gastric secretion is frequently diminished in diabetes mellitus. In pancreatic diabetes the ferments or zymogens are, according to those who have studied them, frequently affected; the pancreatic ferment, the muscular ferment, and the glycolytic ferment are deficient, suppressed or not activated, and glucose does not undergo combustion, but is excreted in the urine.
The few cases that form the basis of this paper were studied with the object of investigating the secretion of pepsin in patients with diabetes mellitus.
As diabetes mellitus is not a common disease, and as digestion is usually good in diabetic patients, one does not have occasion to examine the functions of the stomach in many of these patients. Some of these patients, however, complain of stomach distress, and some other patients have stomach disease, although they
GILBRIDE JJ. THE FUNCTIONS OF THE STOMACH IN DIABETES MELLITUS: WITH SPECIAL REFERENCE TO THE DETERMINATION OF PEPSIN. JAMA. 1911;LVI(7):497–499. doi:10.1001/jama.1911.02560070029010
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