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March 17, 1888


JAMA. 1888;X(11):343-345. doi:10.1001/jama.1888.02400370027010

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Preventive Treatment of Syphilis.  Dr. E. B. Bronson has presented before the Academy of Medicine an able argument, based on theoretical grounds rather than on any practical results as yet achieved, on preventive treatment during the primary stage of syphilis. By preventive treatment, he wished it to be understood, was not necessarily meant abortive treatment, but the employment of such measures as tend in any degree to abridge or mitigate the subsequent course of the infection and its effects upon the constitution. The scheme essentially consists in the local use of antisyphilitics by a method designed to bring the remedy in direct communication with the whole of the affected region in primary syphilis, including more particularly the initial and the diseased inguinal glands. As commonly practiced this regional treatment has been chiefly confined to the use of mercurial hypodermics beneath the initial lesion, unless this was

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