August 4, 1908, I employed the first transfusion in the terminal stages of pellagra. Encouraged by the immediate improvement and rapid recovery in this patient, in collaboration with Dr. Gilman J. Winthrop, I have since transfused nineteen additional patients in the terminal stages of the disease.
Whereas we are unable to draw positive conclusions from this number of cases, we believe that certain valuable deductions may be derived from the statistics which they present. We have endeavored to preserve a spirit of scepticism and unbiased judgment throughout our investigations, and to draw accurate conclusions from the data presented.
Transfusion has been resorted to only in cases in the last stages of pellagra, or steadily retrograding under prolonged and careful treatment by approved therapeutic measures. To illustrate the type of cases in which transfusion has been employed, it is sufficient to state that two patients were moribund at the time of
COLE HP. TRANSFUSION IN PELLAGRA: A REVIEW OF TWENTY CASES. JAMA. 1911;LVI(8):584–585. doi:10.1001/jama.1911.02560080032007
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