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April 14, 1888

THE EARLY RECOGNITION OF EXOPHTHALMIC GOITRE (GRAVES' DISEASE).Read before the Philadelphia County Medical Society, March 14, 1888.

Author Affiliations


JAMA. 1888;X(15):452-455. doi:10.1001/jama.1888.02400410008001a

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In the paper which I have the honor to read to you to-night, I shall not attempt to do more than call your attention to the importance of early recognizing a disorder which often eludes one, to point out certain features which should enable us to do so, and to offer an illustration, very briefly, the salient points in half a score of cases.

Exophthalmic goitre, or Graves' disease, is not a rare malady. At first it is merely a disorder, but frequently becomes a serious disease, and is known to cause death. More often it unfits its victim for active usefulness, or, at least, limits this and sadly disfigures him.

Like certain other ailments the outcome of irreglar nervous discharge, what in its incipiency is a very manageable complaint, produces in time a disastrous effect upon the tissues, and forms a practically unconquerable disease.

Dr. Jonathan Hutchinson says:


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