[Skip to Content]
[Skip to Content Landing]
March 11, 1916


JAMA. 1916;LXVI(11):799-800. doi:10.1001/jama.1916.02580370019007

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


Even with the accumulated knowledge gained from several years' experience in the prolonged administration of nitrous oxid (and oxygen), there is still quite a tendency by some to disregard essential elements of safety, especially when nitrous oxid, administered with normal oxygenation, does not furnish a sufficient depth of anesthesia. Increasing the percentage, and therefore the amount, of nitrous oxid inhaled of course deepens the anesthesia, and this is often a great desideratum; but the increase in the depth of anesthesia thus gained simultaneously decreases the oxygenation, and herein lurks the danger. Most patients can tolerate a decreased oxygenation for a short time, and when one has had experience with this class of patients, the anesthetist thereby becomes emboldened to minimize the danger arising from subnormal oxygenation. Sooner or later, a patient who cannot tolerate even temporarily a decreased oxygenation reaches the service of such an anesthetist, and serious results sometimes

First Page Preview View Large
First page PDF preview
First page PDF preview