During the early part of September, 1910, I personally investigated Ehrlich's work in the treatment of syphilis with salvarsan. I have not made a report earlier, first, because I wished to make some observation of the results obtained by physicians in this country, and to acquire some experience in using the remedy in my own work; and second, because I believed that it would be dangerous to permit the idea to become general that a single dose of salvarsan would permanently cure syphilis.
My own experience with salvarsan, and the observations I have made of this work carried on both in this country and in Europe, lead me to the conviction that under no circumstances should it be used without also using mercury or the iodids. If we can conceive of making a diagnosis of syphilis so early that not a single spirochete has become encapsulated, but all lie free
McKENNA CH. A REPORT ON THE THERAPEUTIC EFFICIENCY OF SALVARSAN. JAMA. 1911;LVI(11):801–803. doi:10.1001/jama.1911.02560110023007
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