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March 11, 1916

Crown Gall and Cancer

Author Affiliations

Bureau of Plant Industry, Laboratory of Plant Pathology, Washington, D. C.

JAMA. 1916;LXVI(11):833. doi:10.1001/jama.1916.02580370053032

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To the Editor:  —Recently I have made discoveries which tie crown gall of plants closer to cancer of man and animals. I can now produce embryonic teratomas at will by bacterial inoculations. All that is necessary is to inoculate growing plants in areas containing dormant totipotent or pluripotent cells, using Bacterium tumefaciens. Moreover, as in man, daughter tumors are produced freely, and these also contain teratoid elements. These results have been obtained repeatedly during the last two months on pelargonium, tomato, tobacco and citrus. A full account will be published within a short time.

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