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March 18, 1911


JAMA. 1911;LVI(11):817-818. doi:10.1001/jama.1911.02560110039020

There is probably no field of science in which greater progress has been made recently than in organic chemistry, and not the least spectacular development of this has been along physiologic lines. Late years have witnessed a fairly adequate solution of the riddle of proteid composition, and in a recent article Kossel,1 himself among the foremost investigators, summarizes the progress made toward the analysis of a similar problem—the composition of the nucleins. Nuclear materials from manifold sources all indicate these substances as the essential element in the composition of the nucleus; and when the importance of the latter is realized in all processes that are considered most peculiarly vital, the value of the study of the nucleins can be appreciated. In general it has been found that these can be split into two main constituents, a proteid and nucleic acid. The former does not differ radically from proteids from