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July 14, 1888

THE IMPUTATIONS ON BETA-NAPHTHOL: Read in the Section on Medicine, at the Thirty-ninth Annual Meeting of the American Medical Association, May, 1888.

Author Affiliations


JAMA. 1888;XI(2):52-53. doi:10.1001/jama.1888.02400540016001c

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Naphthol, as I remarked in a paper read before the Philadelphia County Medical Society, on October 17, 1883, published in The Journal, on November 3, 1883, stands in the same relation to naphthaline as phenol does to benzol and cresol to tuluol. If one of the six molecules of hydrogen in benzol is replaced by hydroxyl, phenol is obtained, and in a similar manner are cresol and naphthol formed. The inference may therefore be safely drawn, through this analogy of formation and similarity of constitution, that their products are similar, and in consequence their general effects, so far as toxic quality is concerned, similar in action on the animal organization. This inference I accordingly drew, and proceeded to experiment with β-naphthol as probably affording a product equally antiseptic and harmless with that offered by the other form.

To do this effectively it was of course neeessary to discard the commercial

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