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March 18, 1916

Constipation in Causation of Epilepsy and Migraine

Author Affiliations


JAMA. 1916;LXVI(12):912. doi:10.1001/jama.1916.02580380062034

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To the Editor:  —Dr. Strate's inquiry (The Journal, Feb. 26, 1916, p. 675) is of the kind precisely calculated to bring out essential facts and straighten out apparent inconsistencies, or, as I prefer to think, to fill out possible omissions in my statement of the causal relationship between constipation and epilepsy. Dr. Strate says: "A symmetrical edema of both internal capsules is of course possible, but shall we say it is probable?" I fancy the answer is to be found in going back to the initial factor in the causation of the disease, and then following sequent phenomena up to the seizure. This, briefly stated, is as follows:

  1. Epilepsy is an infection due to a specific organism, the primary habitat of which is the alimentary canal, more especially the cecum.

  2. Distortions and displacements of the intestines, more especially of the colon and cecum, cause constipation and thereby force the absorption

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