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April 1, 1911


Author Affiliations


From the Department of Ophthalmology, Northwestern University Medical School.

JAMA. 1911;LVI(13):952-953. doi:10.1001/jama.1911.02560130016005

In 1903 Herbert1 discovered the fact that the conjunctival secretion in vernal catarrh is rich in eosinophil polymorphonuclear leukocytes, and called attention to the bearing of this fact in diagnosis. Several observers have confirmed this discovery, in that they found tissue affected with this disease rich in these cells; and Peters2 confirmed it by finding the cells in the secretion. Axenfeld, in his exhaustive study of the pathology of vernal catarrh, emphasized the importance of these cells in diagnosis and reported their presence in eight cases in one year. LaGrange,3 Gabrielides,4 Blaauw5 and Lafon6 have lately recorded cases of this disease with eosinophil cells in the secretion.

In the spring of 1910, two typical cases of vernal catarrh came under my care in which the secretion was rich in eosinophil cells. These two cases attracted my attention to the possibility of the importance of

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