Our variously acquired bits of information concerning the ductless gland disorders lie distractingly before us like the fragments of a modern picture puzzle. Here and there a few pieces, possibly on the basis of similarity of color, have been assembled and fitted together, but the relation of these groups to one another or to the design as a whole is not at all clear. Some of them subsequently prove to have been upside-down; marginal groups are found to belong at the side when they had been thought to go at the top; and the disappointing stage is always reached when pieces appear to have been irrevocably lost. A chance bystander with an eye for form picks up an odd piece, fits it into its proper place, and it immediately becomes apparent from the new outline that two isolated groups or foci of the picture can be articulated. So in the
CUSHING H. THE WEIR MITCHELL LECTURE: SURGICAL EXPERIENCES WITH PITUITARY DISORDERS. JAMA. 1914;LXIII(18):1515–1525. doi:10.1001/jama.1914.02570180001001
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