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October 31, 1914


JAMA. 1914;LXIII(18):1542-1545. doi:10.1001/jama.1914.02570180028006

The time allowed for a paper under the present circumstances will not permit of a full discussion of the subject in hand. I therefore omitted a summary of the literature, the excellent work of others in this field, problems of technic, questions of accidents, etc. I will confine myself to some of the principles involved in blood transfusion and. speak of some of its applications.

When one considers the many facts about the blood, not generally recognized, which are known, and the many facts yet to be learned, one cannot help but realize the complexity of this tissue. Many diseases produce changes in quantity and quality of the blood. Changes in quantity and quality of the blood are responsible for many pathologic conditions. Failure on the part of the blood to modify its quality properly and adequately to meet the required demands in the various conditions is frequently responsible for

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