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Article
October 20, 1888

THE BRADSHAWE LECTURE ON URÆMIA.

JAMA. 1888;XI(16):561-562. doi:10.1001/jama.1888.02400680021003

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Abstract

The Bradshawe Lecture before the Royal College of Physicians this year, by Dr. William Carter, was on a subject of great interest, which was ably handled by the lecturer. Beginning with the definition, "Uræmia may be defined as the altered condition of health caused by the accumulation within the body of poisonous products that should be eliminated by the kidneys," the lecturer points out that the symptoms of this altered condition are so various in themselves, and so variously combined, that within the limits of this general definition what on the surface appear to be altogether different diseases are formed; and it is not surprising that many explanations have been offered of such varying phenomena.

After a careful review of Traube's theory of uræmia, that the nervous symptoms are due to cerebral anæmia, and never occur without preceding cardiac hypertrophy and blood-dilution; that heightened blood-pressure causes cerebral anæmia, and as

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