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Article
November 3, 1888

THE PATHOLOGY OF PERNICIOUS ANÆMIA.

JAMA. 1888;XI(18):633. doi:10.1001/jama.1888.02400700021004

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Abstract

Dr. William Hunter has recently concluded, in the Lancet, a most interesting paper on this subject, being the record of a series of investigations made with the object of throwing some light on the pathology of the disease called progressive anæmia or pernicious anæmia. These investigations were partly clinical and partly pathological. It must be said that Dr. Hunter has occupied himself with a most important task, when we remember the interest taken in this affection since Addison called attention to it.

Space is wanting for more than a summary of the results of the investigations, and some short comment upon them. In the first place, he concludes, pernicious anæmia is to be regarded as a special disease, both clinically and pathologically. It constitutes a distinct variety of idiopathic anæmia. Second. Its essential pathological feature is an excessive destruction of blood. Third. The most important pathological change to be found

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