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November 10, 1888

Ptomaines and Leucomaines, or the Putrefactive and Physiological Alkaloids

JAMA. 1888;XI(19):681. doi:10.1001/jama.1888.04360040033009

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The subject of this volume is one of the greatest interest, for without doubt our knowledge of the causation of disease can be greatly increased by a more detailed knowledge of it. The full importance of ptomaines and leucomaines has been so recently appreciated that as yet many of the facts known to us are so scattered and isolated that a scientific appreciation of them is impossible. The present work will undoubtedly aid much in diffusing a knowledge of these substances in the profession, and in placing before the searchers after new facts all that pertains to the subject up to the present time.

The volume is devoted almost exclusively to the chemistry of these alkaloids. One can not but be impressed with our lack of knowledge of the physiological action of these alkaloids. This is a field widely open to the investigator, and one from which a rich harvest

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