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May 13, 1916


JAMA. 1916;LXVI(20):1552-1553. doi:10.1001/jama.1916.02580460028014

Clinical observations have furnished evidence that in cases of pyloric obstruction an alteration of the usual movements of the stomach may occur. Distention of this organ commonly attends pyloric stenosis, and hypermotility has repeatedly been described as accompanying it. Most of the facts on record have been obtained under conditions in which the stomach was more or less filled with food or otherwise distended, as it frequently is when the pyloric functions are interfered with. The question quite naturally follows as to whether these alterations in motor activity are attributable to the presence of food in the obstructed organ and whether the distention is a factor in the altered muscular performance, or whether the latter is a direct consequence of the pathologic condition involved.

Carlson2 has shown that the "pangs of hunger" are associated with and probably due to rhythmic contractions of the stomach wall, which come on about