In 1899 Dr. Robert B. Greenough and I1 reported on the condition of 187 patients with gastric ulcer treated at the Massachusetts General Hospital for the preceding ten years. We were able to show that "of 114 patients, 80 per cent, were discharged cured or relieved, but at the end of an average period of five years only 40 per cent, remained well." The mortality at the same time (due to gastric disease) was 20 per cent. Among the men it was 30 per cent., in women 9 per cent. The excessive mortality of ulcer among men, its occurrence in life a decade later than in women, and the absence of fatal cases of hemorrhage in women, point to a difference of the ulcer in the two sexes.... The failure of medical treatment to effect a lasting cure in 60 per cent. of the patients indicates the need of
JOSLIN EP. END-RESULTS IN CASES OF GASTRIC AND DUODENAL ULCER. JAMA. 1914;LXIII(21):1836–1839. doi:10.1001/jama.1914.02570210038011
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