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May 20, 1911

Thyroidectin in Exophthalmic Goiter

Author Affiliations

Lake City, Minn.

JAMA. 1911;LVI(20):1497. doi:10.1001/jama.1911.02560200065031

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To the Editor:  —Having read with interest the article on "Treatment of Exophthalmic Goiter with Thyroidectin" (The Journal, April 22, p. 1176) I desire to report one case. I realize fully that one case proves nothing, but I desire to contribute one instance to the sum of collective observation.The patient, Miss H., aged about 35, housekeeper, came for treatment Sept. 1, 1910, presenting a typical case of exophthalmic goiter. The pulse-rate was 140; the neck measured 15 inches in circumference; marked protrusion of the eyes was present, with tremor, heart murmurs, systolic thrill over the thyroid, etc. The thyroid gland was the size of an average hen's egg, central and uniform in shape. The patient was given thyroidectin 5 gr. capsules three a day, one after each meal. This was continued to October 10, about six weeks, with no discoverable improvement in any way. On the suggestion of a

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