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July 27, 1889


JAMA. 1889;XIII(4):140-143. doi:10.1001/jama.1889.04440030032010

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Yellow Fever—Unprecedented Severity of Epidemic of 1889—Can true Yellow Fever pass the Coast Range and become Epidemic in the Uplands of the Interior?—Influence of bad Sanitary Conditions—Does Freire's Inoculation of the Attenuated Microbe Protect?—Sudden Deaths—Beriberi.

It is quite certain that since the epidemic which devastated Memphis in 1878, nothing has happened in the history of yellow fever so severe as that which has decimated Santos and Camfinas this year.

The epidemic in Rio de Janeiro presents few new features, and the frequency with which the city is. visited by yellow fever, its commercial importance and rapid and frequent communication between it and the States, place the matter within easy reach of your readers. Not so with Santos and Camfinas.

Santos is, after Rio, the most important of the coffee ports. A city of about 20,000 souls, situated just within the tropics, it is almost entirely surrounded by water; in fact,

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