During the past few months we have had occasion to observe the immediate effect clinically following the intraspinal injections of different preparations of mercury. Before presenting our observations in a limited number of cases it may be of interest to call attention to similar uses of mercury by other authorities.
Sicard,1 in 1913, reported the use of mercuric cyanid in doses of from 0.1 to 0.2 mg. combined with 1.5 cg. of novocain in 2 c.c. of normal salt solution raised to a temperature of 100 C. and injected intraspinally. He employed this preparation, stating that it did not precipitate the albumins, and that with these small doses the reaction was very marked as employed in cases of tabes and meningomyelitis. The general paretics did not show so marked a reaction even after doses of from 0.4 to 0.5 mg. At the same time the latter cases did not
HALL GW, CULBERTSON H, SLAGHT C. REACTIONS FOLLOWING INTRASPINAL INJECTIONS OF MERCURY. JAMA. 1916;LXVI(26):2062–2063. doi:10.1001/jama.1916.02580520018005
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