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December 19, 1914


JAMA. 1914;LXIII(25):2190-2194. doi:10.1001/jama.1914.02570250020006

The treatment of certain obstinate diseases of the skin by human serum is a therapeutic measure of comparatively recent date. In view of some of the favorable reports on this method it seems strange that it has not been given a more extended trial, especially in America. Although the present report is limited to the treatment of one disease, psoriasis, by a single method of serum therapy, it may be of interest to say a few words on the general subject of the use of human serum in treating skin diseases.

In December, 1910, a communication was published by Mayer and Linser1 on the result of treatment of a case of herpes gestationis by injections of serum obtained from another pregnant woman. The theoretic basis which led Mayer to suggest this therapeutic trial was as follows: During pregnancy certain poisonous substances are supposed to enter the maternal circulation from

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