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December 26, 1914


JAMA. 1914;LXIII(26):2293-2294. doi:10.1001/jama.1914.02570260029021

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Although the nature of the supply of vasomotor nerves to the kidney and the conditions which bring them into activity are fairly well known, additional factors which may control the flow of urine are far from being completely elucidated. Most writers on the physiology of the kidneys deny the existence of specific secretory nerves for these organs, although Asher and Pearce have suggested that the vagus and splanchnics are direct secretory nerves to them. There is a tendency in some quarters to postulate the occurrence of specific chemical excitants or diuretics, formed in the body and acting as do the group of stimulants now classed as hormones.

Experimenters who have busied themselves with the physiology of the renal secretion have at times been brought face to face with contradictions which they could not explain on a purely vasomotor basis, that is, by corresponding alterations in the blood-supply. In the course

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