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August 12, 1916


JAMA. 1916;LXVII(7):514-515. doi:10.1001/jama.1916.02590070038015

The causation of endemic goiter has furnished a topic of engrossing interest which gains prominence in the United States as newer areas of the noticeable distribution of this disease are being brought to the attention of students of the medical sciences. At one time considerable credence was given to the assumed correlation between the geologic formation ofcertain regions and the incidence of thyroid growths. The strata were believed to contain and yield to the waters issuing from them undefined substances that are noxious in the sense of inducing thyroid hyperplasia. Although this broader contention, supported by the assertions of the Birchers, has been quite generally abandoned, the possibility of some etiologic connection between potable waters and endemic goiter has continued to clamor for recognition up to present day. If water is not the vehicle for a defined chemical substance, it may conceivably be a carrier of biologic agencies, such as