The epidemic of poliomyelitis that is prevailing at the present time so extensively in New York and in some degree widely throughout the United States has led to many inquiries being made regarding the serum treatment of the disease, and particularly of the stage to which the treatment has advanced. This brief paper is intended not only to answer such inquiries, but also to provide a basis for the wider employment of the treatment where the difficult conditions surrounding the obtaining of immune human serum can be surmounted.
It was demonstrated by Flexner and Lewis,1 and afterward confirmed by several investigators, that monkeys which had recovered from an attackof poliomyelitis induced experimentally were not subject to successful reinoculation with the virus of the disease. This was followed by the detection by Römer and Joseph2 and later by others in the blood of such resistant or protected monkeys, and
FLEXNER S. A NOTE ON THE SERUM TREATMENT OF POLIOMYELITIS (INFANTILE PARALYSIS). JAMA. 1916;LXVII(8):583–584. doi:10.1001/jama.1916.02590080033013
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