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The literature of the surgical treatment of affections in the ileo-cæcal region has been increasing very rapidly during the last few years. A great deal has been said and written concerning the propriety of surgical interference in cases of perforative appendicitis, typhlitis, paratyphlitis and perityphlitis. Post-mortem examination and clinical experience have demonstrated that with few exceptions localized and diffuse peritonitis as well as suppurative inflammation of the connective tissue originating in the ileo-cæcal region, are caused by an antecedent affection of the appendix vermiforniis, which has resulted in perforation or gangrene of that structure. While it cannot be said that unanimity of opinion exists among surgeons in reference to the exact indications for operative treatment in cases of appendicitis and suppurative perityphlitis, it is safe to assert that the majority of them would not hesitate to resort to the knife in every instance where it would be possible to ascertain
SENN N. A PLEA IN FAVOR OF EARLY LAPAROTOMY FOR CATARRHAL AND ULCERATIVE APPENDICITIS, WITH THE REPORT OF TWO CASES. JAMA. 1889;XIII(18):630–636. doi:10.1001/jama.1889.02401140016002a
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