It is now almost four years since I first began to study the contents of the duodenum as a means of diagnosis in various conditions of pathologic interest. During this time, over 120 analyses have been made; included in this series is a group of fifty-two cases which presented the common symptom of jaundice. As the number and variety of these cases of icterus increased, it became more and more obvious that there existed in the duodenal tube a valuable instrument for gathering additional data bearing on the differential diagnosis of these conditions. It is logical and rational that a tube which can enter the duodenum and rest opposite the exit of the bile and pancreatic ducts should bring home most instructive data pertaining to the patency or non-patency of these structures. As the disease processes that cause the varieties of jaundice vary in each type of case, just so
CROHN BB. THE CHEMICAL EXAMINATION OF DUODENAL CONTENTS AS A MEANS OF DIAGNOSIS IN CONDITIONS OF JAUNDICE. JAMA. 1915;LXIV(7):565–569. doi:10.1001/jama.1915.02570330013004
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