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February 13, 1915


JAMA. 1915;LXIV(7):596. doi:10.1001/jama.1915.02570330044021

It requires little argument to emphasize the great scientific importance of learning as much as possible respecting the chemical composition of the circulating blood. A precise knowledge of the make-up of this fluid would serve to tell a good part of the story of tissue metabolism. Investigators have long realized the inherent difficulties both in detecting and in determining quantitatively various constituents of the blood, owing to the minute amounts in which they are present in a unit volume of the circulating medium at any moment. One hundred c.c. of blood — a large quantity to furnish at once — ordinarily contain not more than 0.1 gm. of sugar. Yet even this small content renewed or discharged from moment to moment in the course of the circulation may represent the exchange of no inconsiderable total amount of carbohydrate in the course of a few hours.

Other constituents are present in