So much is continually appearing in medical journals on the subject of enuresis nocturna, and so many remedies are being recommended as wholly reliable and efficacious in its treatment, that it would appear almost superfluous for us to refer to it. And yet, if we examine all this literature, we will see that it has a very one-sided aspect; that (except in cases arising from reflex irritation or organic lesions, whose treatment is indicated by the discovery of such a cause—a class which we do not propose to consider here) nearly all of the remedies advised are used either empirically, or their use is based on the idea that the origin is invariably, as Trousseau declared, a neurosis, an excessive irritability, or exaggerated tonicity of the muscular fibres of the bladder, subservient to a hypersensitive condition of the mucous membrane of the organ; and the little sufferers are accordingly dosed
A NEGLECTED PHASE OF ENURESIS NOCTURNA. JAMA. 1889;XIII(22):779–781. doi:10.1001/jama.1889.02401180021005
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