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December 14, 1889

THE ETIOLOGY OF TYPHOID FEVER.Read in the Section of the Practice of Medicine, Materia Medica and Physiology, at the Fortieth Annual Meeting of the American Medical Association, June, 1889.

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JAMA. 1889;XIII(24):831-837. doi:10.1001/jama.1889.02401200001001

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Mr. Chairman and Gentlemen of the Section:—As my time is limited I shall waste no words in introductory remarks, but shall endeavor to get at the gist of my subject immediately. In 1880 Prof. C. J. Eberth, of Zurich, in eighteen out of forty cases of typhoid fever, found in sections of the spleen and mesenteric glands a bacillus which is distinguished from the ordinary putrefactive bacilli by the difficulty with which it takes up the analine stains. At the same time Eberth reported that in twenty-four similar examinations of those dead from other diseases he was unable to detect this bacillus. From these facts the distinguished Swiss investigator thought himself entitled to claim that he had discovered the true germ of typhoid fever. Even before Eberth's report appeared, Koch had seen and photographed the same bacillus, so that this germ is by some called the Eberth bacillus and by

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