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December 21, 1889


JAMA. 1889;XIII(25):885-886. doi:10.1001/jama.1889.04440070019007

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An Epidemic of Ulcerative Vaccinia.—At a recent meeting of the Académie de Médecine, M. Hervieux reported the results of his investigations, relative to the appearance of ulcerative vaccinia among the school children of Motteaux Bois. Of thirty-eight children vaccinated thirty-seven presented the abnormal symptoms observed; these symptoms as they appeared on the thirteenth day after vaccination, consisted of intense inflammatory action, abundant suppuration, lymphangitis, œdema, fever and delirium. The period of incubation was eight, ten and twelve days. Six weeks after vaccination, nearly all of the children had entirely recovered. The virus was obtained from a boy 9 years of age, who presented an entirely healthy appearance with the exception of lymphatic enlargements affecting the axillary, submaxillary and cervical glands. The boy's parents appeared healthy, but refused to submit to close inspection. A diagnosis of syphilitic infection was first made by the physicians who examined the cases, but this

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