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March 20, 1915


Author Affiliations

Professor of Tropical Medicine; Assistant Professor of Pathology BOSTON

JAMA. 1915;LXIV(12):965-968. doi:10.1001/jama.1915.02570380013004

PREVIOUS INVESTIGATIONS  We have not been able to find in the literature any accurate and complete description of the pathologic anatomic lesions of Oroya fever. Evidently but very few careful and complete necropsies have been performed in those regions in which the disease occurs endemically. Moreover, the disease often has been confused with other diseases which occur in these localities. Both of these facts tend to explain the absence in the literature of complete and accurate descriptions of the lesions which occur in Oroya fever. In the estimable monograph of Professor Odriozola,1 we find the most complete account of the gross lesions, and Scheube,2 Plehn3 and Castellani4 also very briefly refer to the pathologic anatomy of the disease.Odriozola, writing on this subject, states that the lesions which are observed at necropsy are relatively slight when compared with the gravity of the disease. The most noticeable