DRUGS WHICH STIMULATE SYMPATHETIC ENDINGS
Oliver and Schaefer investigated the actions of extract of the suprarenal gland previous to the isolation of an active principle by Abel in 1897. This active principle has been prepared by many workers, by whom it has been given different names, including "epinephrin," "suprarenalin," "supracapsulin," "adrenin" and "adrenalin," the last being the commercial name by which it is commonly known. The synthetic preparation has likewise received a number of names, including "homorenon" and "l-suprarenin synthetic."The epinephrin obtained from the gland is levorotary, but the artificial is either levorotary or dextrorotary, or it may consist of a mixture of these two. Levorotary epinephrin is of uniform activity, so long as it has not undergone decomposition, to which it is prone, whether it is derived from the gland or prepared artificially. The market supply of artificial epinephrin is levorotary.Dextrorotary epinephrin is only about
PRACTICAL PHARMACOLOGY. JAMA. 1915;LXIV(17):1396–1399. doi:10.1001/jama.1915.25710430001012
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