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December 2, 1916

Formula and Preparation of Dakin's Solution

JAMA. 1916;LXVII(23):1687. doi:10.1001/jama.1916.02590230051025

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To the Editor:  —The formula for the preparation of Dakin's solution which you give in The Journal, Oct. 7, 1916, has recently been superseded by the following which I obtained from Dr. Carrel at Compiègne last May.The unsatisfactory results sometimes obtained by the use of the original preparation, and the disfavor which it has acquired in the hands of some surgeons are probably due to imperfections in the product, such as the persistence of alkalinity. Some of the wounds which I saw in various hospitals under the treatment were brown and unnatural in appearance, while all at Compiègne were rosy and apparently entirely free of pus. The wounds were there kept constantly wet with the solution, which was introduced through tubes and poured on the surface every two hours.It is desirable that the determination of its value should not be delayed by defects of preparation, and you may

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