During the autumn of 1915, the supply of salvarsan and neosalvarsan in the United States became exhausted. There was none to be had except that in the hands of speculators, who demanded extraordinary prices for the drug.
In the spring of 1916, the agents Farbwerke-Hoechst Company of New York succeeded, after months of effort, in obtaining a shipment from Germany. Shortly after the arrival of this importation, we received a supply of salvarsan direct from the New York agents, and resumed the use of it in the routine treatment of syphilitic patients with the same technic which we had formerly employed.
The water used is distilled in Jena glassware from distilled water furnished by the Consumers' Company. Each morning the water is distilled and collected in Jena flasks of 500 c.c. capacity. The flask is capped with gauze, then put over the flame and kept there until the boiling point
Ormsby OS, Mitchell JH. TOXICITY OF THE PRESENT SUPPLY OF SALVARSAN AND NEOSALVARSAN. JAMA. 1916;LXVII(24):1756. doi:10.1001/jama.1916.25910240005014d
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