[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 34.204.200.74. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
December 16, 1916

AN EXPERIMENTAL RESEARCH INTO THE NATURE OF NITROUS OXID AND OF ETHER ANESTHESIA: WITH SPECIAL REFERENCE TO CERTAIN EFFECTS ON THE ORGANS OF THE BODY, AND CERTAIN RELATIONS TO NORMAL SLEEP, HYDROGEN-ION CONCENTRATION AND INFECTIONS

Author Affiliations

Fellow of the American College of Surgeons CLEVELAND

JAMA. 1916;LXVII(25):1830-1831. doi:10.1001/jama.1916.02590250032010
Abstract

If we view man and the lower animals as adaptive mechanisms, governed by the universal laws of physics and chemistry, then we must believe that every phase of human or animal behavior is occasioned by and in turn occasions physical and chemical changes in the body. Therefore an understanding of the vast alterations in the behavior of the anesthetized organism— changes which may range from the slightest depression of mental power through progressively deeper stages of unconsciousness to death, necessitates a search for the physical and chemical changes caused by the anesthetic. Accordingly, in this study we shall consider (a) the gross behavior of the anesthetized individual in a consideration of the relation of anesthesia to normal sleep; (b) the influence of ether and of nitrous oxid on the histologic structure of certain organs; (c) the relation of ether and of nitrous oxid to the hydrogen-ion concentration of the blood

First Page Preview View Large
First page PDF preview
First page PDF preview
×