The subject of the treatment of fibromas of the uterus by non-surgical methods is one of such importance, that all data having a bearing on the subsequent behavior of such growths should be carefully recorded. The time must of necessity be very great which must lapse in any individual case, before the final evidence can be secured as to the subsequent degenerations, for example, after the application of the Roentgen ray or radium. Of peculiar importance is the question whether the sarcomatous or other forms of malignant degeneration are less liable to occur after such treatment, or whether they occur at all.
While no exact percentage can be given, it is certain that sarcomatous degeneration is a definite risk in untreated fibroma of the uterus.
Many series of reports, especially those of aggregates made up from many sources, are almost without statistical value, as for a long time in many
SHOEMAKER GE. SARCOMATOUS DEGENERATION OF A UTERINE FIBROMA FIVE YEARS AFTER ROENTGEN-RAY TREATMENT FOR PRESSURE AND HEMORRHAGE. JAMA. 1915;LXIV(20):1653–1654. doi:10.1001/jama.1915.02570460029012
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