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During the last few years the conception of the elemental functions of the heart muscle has undergone radical change, and a fuller comprehension of the causes of infections of the heart has resulted from the work of such observers as Poynton and Payne, Billings, Rosenow, Libman, Baehr, Schottmüller and others. The pathologic changes present in the heart in extracardial and cardiac infections have received attention at the hands of a number of writers, and the symptomatology of myocardial changes in heart affections of an inflammatory origin have been extensively elucidated, particularly by Mackenzie. But the pathology of the living heart and its changing symptomatology during the course of an inflammation are not yet thoroughly understood. On an intimate knowledge of the vital pathology of the inflamed heart depends naturally proper conception of treatment of its infections, and it certainly seems that attention to manifestations of the earliest lesions in bacterial
EBRIGHT GE. INFECTIOUS ENDOCARDITIS. JAMA. 1916;LXVII(26):1927–1928. doi:10.1001/jama.1916.02590260043013
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