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May 29, 1915


Author Affiliations


From the University of Pittsburgh, School of Medicine.

JAMA. 1915;LXIV(22):1823-1824. doi:10.1001/jama.1915.02570480019007

Transplantation of human ovarian tissue with varying degrees of success has been reported and is occasionally practiced. For the most part the operation has been performed with a view of preservation of its internal secretory function. Many case histories have been reported which indicate that in this way the operation is frequently successful. In 1906 Morris1 reported the birth of a child in a woman from whom the ovaries were removed and in whom ovaries from another woman were engrafted four years previously.

For general biologic reasons, but particularly with the view of studying heredity, numerous attempts have been made to engraft ovarian tissue into animals and birds. Prior to 1894, Romanes2 made many experiments in endeavoring to transplant ovaries in rabbits and dogs. His results were uniformly unsuccessful.

Gregorieff3 in 1897 reported pregnancy in four rabbits from which the ovaries were removed and replaced.


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