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To the Editor:
—May I add my experience in corroboration of your statement in a recent Current Comment, on this subject (The Journal, May 15, 1915, p. 1664) that the fever of typhus terminates in a great proportion of cases by lysis and not by crisis? The three typhus epidemics which I observed in Russia have given me sufficient material to support that statement. As a rule, the fever terminates on the twelfth, fourteenth or seventeenth day, the drop in temperature occupying from twelve to seventy-two hours. Even in the rare cases in which the fever ends abruptly, the temperature curve is seldom like the typical curve of lobar pneumonia. It may be worth mentioning that in children in whom the disease is nearly always mild, critical defervescence hardly ever occurs.
Friedman GA. The Defervescence in Typhus Fever. JAMA. 1915;LXIV(22):1867. doi:10.1001/jama.1915.02570480063027
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