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Article
January 6, 1917

Lister on the Use of Animals in Research

JAMA. 1917;LXVIII(1):53. doi:10.1001/jama.1917.04270010053019

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Abstract

My dear Sir:  —I am grieved to learn that there should be even a remote chance of the legislature of any state in the Union passing a bill for regulating experiments upon animals.It is only comparatively recentlyl in the world's history that the gross darkness of empiricism has given place to more and more scientific practice, and this result has been mainly due to experiments upon living animals. It was to these that Harvey was in large measure indebted for the fundamental discovery of the circulation of the blood, and the great American triumph of general anesthesia was greatly promoted by them. Advancing knowledge has shown more and more that the bodies of the lower animals are essentially similar to our own in their intimate strucutre and functions, so that lessons learnt from them may be applied to human pathology and treatment. If we neglect to avail ourselves of

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