Head and Campbell1 have shown that the peripheral manifestations in herpes zoster are due to lesions in the corresponding posterior root ganglia. The character of the lesions in the ganglia described by them and others and the symptoms suggest strongly a microbic origin of this disease. And recently Sunde2 has demonstrated gram-staining diplococci in a hemorrhagic gasserian ganglion in a case of ophthalmic herpes in an old man who died of a bronchopneumonia three and one-half days after the appearance of the herpes. The evidence, therefore, that bacteria are the cause of the lesions in the ganglia is rather direct, but so far herpes has not been produced experimentally in animals by intravenous injection.
Rosenow3 has demonstrated that streptococci from the appendixes in appendicitis, from the walls of the gallbladder and the center of gallstones in cholecystitis, from the depths of ulcers of the stomach and duodenum,
ROSENOW EC, OFTEDAL S. THE ETIOLOGY AND EXPERIMENTAL PRODUCTION OF HERPES ZOSTER: PRELIMINARY NOTE. JAMA. 1915;LXIV(24):1968. doi:10.1001/jama.1915.02570500016005
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