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January 27, 1917


JAMA. 1917;LXVIII(4):267-273. doi:10.1001/jama.1917.04270010267009

This is intended to be a brief paper, and few references will be given. The literature of syphilis of the nervous system is now so extensive that it properly falls into various categories, though sharp divisions are not always made into clinical, serologic, etc. We seem to be no nearer a valid line of distinction between paresis and cerebrospinal syphilis than we were, and most authors are becoming very cautious in their assertions as to what does and shat does not constitute paresis. There is no reason to suppose that there is any essential difference in the spirochetes in these two conditions, but there is experimental evidence to sustain the view that the spirochete which attacks principally the brain is somewhat different from the one which cripples the heart or assails the liver, as witness a recent communication from the Army Medical School to Dr. Archibald Church.1

On anatomic

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