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February 10, 1917


JAMA. 1917;LXVIII(6):420-425. doi:10.1001/jama.1917.04270020100006

My researches on interstitial gingivitis and pyorrhea alveolaris1 were published in book form in 1899. In this work every conceivable phase of the disease was studied on animals as well as man. The pathology was beautifully illustrated from its beginning to the formation of abscess, on the one hand, and exfoliation of the teeth, on the other.

The object of this paper is to try to make clear the etiology, pathology and treatment based on the researches laid down in my work.

The tissues about the roots of the tooth may become diseased under extreme local irritation or from constitutional disease, but as a rule the progress of tissue building about the first and second set of teeth prevents tissue degeneration. Not until the bone has obtained its growth, from 27 to 35 years of age, does degeneration take place to any great extent, although marked inflammation of the

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