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July 14, 1917


JAMA. 1917;LXIX(2):124. doi:10.1001/jama.1917.02590290046018

The circumstances which result in a nearly constant body temperature as the result of an accurate balance of heat production and heat loss in the organism are, to say the least; highly suggestive of some regulatory process on the part of the central nervous system. Starling4 has remarked that whether this function of temperature regulation can be specially localized at any part of the central nervous system, so that it would be possible to speak of a heat center in the same way as we speak of a respiratory or vasomotor center, is doubtful.

It has been suggested that the thermogenic center — that responsible for regulating heat production — is situated at a lower level than the thermotaxic system which presides over and determines the balance between heat production and heat loss. Barbour5 of the Yale University School of Medicine, while admitting that we may not give

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